Genetically engineered T cells that express chimeric antigen receptors (CAR+) are heterogeneous and thus, understanding the immunotherapeutic efficacy remains a challenge in adoptive cell therapy.We developed a high-throughput single-cell methodology, Timelapse Imaging Microscopy LIP SHINE WHISPER In Nanowell Grids (TIMING) to monitor interactions
Introduction: The dorsal striatum plays an important role in the control of motor activity and learning processes within the basal ganglia circuitry.Furthermore, recent works have suggested functional differentiation between subregions of the dorsal striatum Methods: The present study examined the effects of bilateral electrolytic lesions of the do
Mesenteric venous thrombosis is a rare cause of chronic pain in abdomen.Only in few cases with abdominal pain, bowel infarct has been reported.This report is that of a 42-year-old male with a history of chronic alcoholism, presented with continuous dull pain in Maori Design Guitar Straps abdomen for 1 year and vomiting for 1 month, typically after
Vaccination to prevent influenza virus infection and to lessen its severity is recommended among healthcare workers (HCWs).Health professionals have a higher risk of exposure to viruses and could transmit the influenza virus to vulnerable patients who are prone to severe disease and mortality.The aim of the current study was to evaluate the levels
The standard of care for treatment of glioblastoma results in a mean survival of only 12 to 15 months.Convection-enhanced delivery (CED) is an investigational therapy to treat glioblastoma that utilizes locoregional drug delivery via a small-caliber catheter placed into the brain parenchyma.Clinical trials have failed to reach their endpoints due t